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Tegaserod Maleate
(British Approved Name Modified, US Adopted Name, rINNM) Drug Nomenclature Synonyms: HTF-919; SDZ-HTF-919; Tegaserod, maleato de BAN: Tegaserod Maleate [BANM] USAN: Tegaserod Maleate INN: Tegaserod Maleate [rINNM (en)] INN: Maleato de tegaserod [rINNM (es)] INN: Tégasérod, Maléate de [rINNM (fr)] INN: Tegaserodi Maleas [rINNM (la)] INN: Тегасерода Малеат [rINNM (ru)] Chemical name: 1-{[(5-Methoxyindol-3-yl)methylene]amino}-3-pentylguanidine maleate Molecular formula: C16H23N5O,C4H4O4 =417.5 CAS: 145158-71-0 (tegaserod); 189188-57-6 (tegaserod maleate) ATC code: A03AE02 Stability and compatibility. Crushed tablets of tegaserod were found to be stable in water, and apple juice the latter may mask the taste of the drug. Orangejuice, milk, or yogurt were not recommended as vehicles because of incomplete dissolution or uncertainty about stability. Adverse Effects The most common adverse effects of tegaserod are gastrointestinal disturbances including abdominal pain, diarrhoea, nausea, vomiting, and flatulence. Diarrhoea generally occurs within the first week of treatment and is usually transient … Read entire article »
Filed under: Medications
Sodium Picosulfate
(British Approved Name, rINN) Drug Nomenclature International Nonproprietary Names (INNs) in main languages (French, Latin, Russian, and Spanish): Synonyms: DA-1773; LA-391; Nátrium-pikoszulfát; Natrii Picosulfas; Natrii Picosulfas Monohydricus; Natrio pikosulfatas; Natriumpikosulfaatti; Natriumpikosulfat; Picosulfato de sodio; Picosulphol; Pikosíran sodný monohydrát; Sodium Picosulphate BAN: Sodium Picosulfate INN: Sodium Picosulfate [rINN (en)] INN: Picosulfato de sodio [rINN (es)] INN: Picosulfate de Sodium [rINN (fr)] INN: Natrii Picosulfas [rINN (la)] INN: Натрия Пикосульфат [rINN (ru)] Chemical name: Disodium 4,4´-(2-pyridylmethylene)di(phenyl sulphate) Molecular formula: C18H13NNa2O8S2,H2O =499.4 CAS: 10040-45-6 ATC code: A06AB08 Read code: y01Ru; y07d4 Pharmacopoeias. In Europe and Japan. European Pharmacopoeia, 6th ed. (Sodium Picosulfate). A white or almost white, crystalline powder. Freely soluble in water slightly soluble in alcohol. Adverse Effects and Precautions As for Bisacodyl. Bowel evacuation. Sodium picosulfate with magnesium citrate was considered a safe and effective bowel cleansing agent in adults and children with inflammatory bowel … Read entire article »
Filed under: Medications
Polycarbophil
(British Approved Name, rINN) Drug Nomenclature INNs in main languages (French, Latin, Russian, and Spanish): BAN: Polycarbophil INN: Polycarbophil [rINN (en)] INN: Policarbofilo [rINN (es)] INN: Polycarbophile [rINN (fr)] INN: Polycarbophilum [rINN (la)] INN: Поликарбофил [rINN (ru)] CAS: 9003-97-8 Read code: y01Ee Pharmacopoeias. In US. The United States Pharmacopeia 31, 2008 (Polycarbophil). It is polyacrylic acid cross-linked with divinyl glycol. White to creamy-white granules, with a characteristic, ester-like odour. Swells in water to a range of volumes, depending primarily on the pH. Insoluble in water, in common organic solvents, and in dilute acids and alkalis. A 1 % mixture in water has a pH of not more than 4.0. Store in airtight containers. Polycarbophil Calcium Drug Approvals (British Approved Name Modified, rINNM) International Nonproprietary Names (INNs) in main languages (French, Latin, and Spanish): Synonyms: AHR-3260B; Policarbofilo cálcico; Polycarbophilum Calcii; Polykarbofiilikalsium; Polykarbofilkalcium; Polykarbophilum Calcicum; Wl-140 BAN: Polycarbophil … Read entire article »
Filed under: Medications
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