Movicol Macrogol 3350, sachet containing 13.125 g powder, 30, Movicol; sachet containing 6.563 g powder, 30, Movicol-Half Purpose of Application To seek the following: a. an extension to the current listing to include the treatment of faecal impaction in adults, where conventional therapies have failed, and the alternative treatments may require hospitalisation; and b. a similar listing for a lower strength product that can be used in adults and children for the treatment of faecal impaction, where conventional therapies have failed, and the alternative treatments may require hospitalisation. Background At the June 2002 PBAC meeting, Macrogol 3350 (13.125 g, sachet) was recommended for a restricted benefit listing for the treatment of constipation in patients with malignant neoplasia, on the basis of acceptable cost-effectiveness compared to lactulose. PBS listing was implemented on 1 November 2002. Registration Status Movicol is TGA approved for the following indications: • treatment of constipation. • faecal impaction, defined as refractory constipation with faecal loading Read more [...]

Senna is an anthraquinone stimulant laxative that is used to treat constipation and for bowel evacuation before investigational procedures or surgery. Preparations UK: Ex-Lax; Nylax with Senna; Senokot; Sure-Lax US: Black-Draught; Dosaflex; Dr Edwards Olive; Evac-U-Gen; Ex-Lax; Fletchers Castoria; Lax Pills; Little Tummys Laxative; Maximum Relief Ex-Lax; Senexon; Senna Smooth; Senna-Gen; Senokot; Senokotxtra; X-Prep Drug Nomenclature Synonyms: Alexandriai szenna termés (senna pods, Alexandrian); Plod kasie úzkolisté (senna pods, Tinnevelly); Plod kasie ostrolisté (senna pods, Alexandrian); Sen; Senų lapai (senna leaf); Senų vaisiai (senna pods, Alexandrian); Sennabalja, Tinnevelley- (senna pods, Tinnevelley); Sennabalja, alexandrinsk (senna pods, Alexandrian); Sennanpalko, Aleksandrian (senna pods, Alexandrian); Sennanpalko, Tinnevelleyn (senna pods, Tinnevelley); Sennový list (senna leaf); Siauralapių senų vaisiai (senna pods, Tinnevelly); Szennalevél (senna leaf); Tinevelly szenna termés (senna pods, Tinnevelly) CAS: 8013-11-4 ATC code: A06AB06 Read code: y01Rq Description. Read more [...]

Magnesium hydroxide is also given as an osmotic laxative in oral doses of about 2 to 5 g. Preparations United Kingdom: Milk of Magnesia; United States: Dulcolax; Milk of Magnesia; Phillips' Chewable; Phillips' Milk of Magnesia Drug Nomenclature Synonyms: E528; Hydroxid hořečnatý; Magnézium-hidroxid; Magnesii Hydroxidum; Magnesio, hidróxido de; Magnesium Hydrate; Magnesiumhydroksidi; Magnesiumhydroxid; Magnio hidroksidas Molecular formula: Mg(OH)2 =58.32 CAS: 1309-42-8 ATC code: A02AA04; G04BX01 Read code: y01SB [Laxative]; y03Lp Note. Compounded preparations of magnesium hydroxide may be represented by the following names: • Co-magaldrox x/y (BAN) — where x and_y are the strengths in milligrams of magnesium hydroxide and aluminium hydroxide respectively. Pharmacopoeias. In Europe, International, US. European Pharmacopoeia, 6th ed. (Magnesium Hydroxide). A fine white or almost white amorphous powder. Practically insoluble in water dissolves in dilute acids. A solution in water is alkaline to phenol-phthalein. The United States Pharmacopeia 31, 2008 (Magnesium Read more [...]

Bisacodyl is a diphenylmethane stimulant laxative used for the treatment of constipation and for bowel evacuation before investiga-tional procedures or surgery. Preparations UK: Biolax; Dulcolax; Entrolax US: Alophen; Bisa-Lax; Correctol; Doxidan; Dulcolax; Evac-Q-Tabs; Ex-Lax Ultra; Feen-A-Mint; Fleet Bisacodyl; Fleet Laxative; Gentlax; Modane Drug Approvals (British Approved Name, rINN) International Nonproprietary Names (INNs) in main languages (French, Latin, and Spanish): Bisacodilo; Bisacodylum; Bisakodil; Bisakodilis; Bisakodyl; Bisakodyyli; Biszakodil. BAN: Bisacodyl INN: Bisacodyl [rINN (en)] INN: Bisacodilo [rINN (es)] INN: Bisacodyl [rINN (fr)] INN: Bisacodylum [rINN (la)] INN: Бисакодил [rINN (ru)] Chemical name: 4,4´-(2-Pyridylmethylene)di(phenyl acetate) Molecular formula: C22H19NO4 =361.4 CAS: 603-50-9 (bisacodyl); 1336-29-4 (bisacodyl tannex) ATC code: A06AB02; A06AG02 Read code: y01RZ Pharmacopoeias. In China, Europe, Japan, and US. European Pharmacopoeia, 6th ed. (Bisacodyl). A white or almost white crystalline powder. Practically insoluble Read more [...]

Lactulose is a synthetic disaccharide osmotic laxative used in the treatment of constipation and in hepatic encephalopathy. Preparations UK: Duphalac; Lactugal; Lemlax; Regulose US: Cephulac; Cholac; Chronulac; Constilac; Constulose; Duphalac; Enulose; Kristalose Drug Approvals (British Approved Name, US Adopted Name, rINN) Synonyms: Lactulosa; Lactulosum; Laktulóz; Laktuliozė; Laktuloosi; Laktulos; Laktulosa BAN: Lactulose USAN: Lactulose INN: Lactulose [rINN (en)] INN: Lactulosa [rINN (es)] INN: Lactulose [rINN (fr)] INN: Lactulosum [rINN (la)] INN: Лактулоза [rINN (ru)] Chemical name: 4-O-β-d-Galactopyranosyl-d-fructose Molecular formula: C12H22O11 =342.3 CAS: 4618-18-2 ATC code: A06AD11 Pharmacopoeias. In Europe and Japan. China only contains specifications for a solution. US only contains specifications for a solution and a concentrated liquid. European Pharmacopoeia, 6th ed. (Lactulose). A white or almost white, crystalline powder. Freely soluble in water sparingly soluble in methyl alcohol practically insoluble in toluene. European Pharmacopoeia, 6th Read more [...]